|
KMID : 0978920090100020193
|
|
Korean Journal of Clinical Geriatrics
2009 Volume.10 No. 2 p.193 ~ p.203
|
|
|
The Relationship between Kyphosis and Gastro-Esophageal Reflux Disease (GERD) in the Elderly
|
|
Kim Sung-Hoon
Lee Yang-Gyun
Hong Sung-Ho
Oh Mi-Kyeong
Cho Choo-Yon
|
|
|
Abstract
|
|
|
Background: Gastro-esophageal relux disease (GERD) deteriorates the quality of life by causing various complications. It is known that it gets worse as the patients are older, and its prevalence rate in Korea is increasing recently. Also, the prevalence rate of kyphosis increases with age. We believe there is a correlation between kyphosis and GERD from the fact that other diseases with increasing intra-abdominal pressure show correlation with GERD. Invasive methos of evalution such as gastroduodenoscopy is required in diagnosing GERD in the elderly, because often the symptoms are insignificant compare to the extent of the disease. For this reason, more non-invasive method of predicting GERD is necessary. Consequently, in this paper, authors investigated the relationship between kyphosis and GERD (reflux esophagitis, hiatal hernia) in the elderly, and searched for other factors that affect GERD for the elderly.
Methods: Gastroduodenoscopy and thoracic or chest lateral radiographs were carried out operated to check for reflux esophagitis (RE) and hiatal hernia (HH), and the Cobb angle which show the grade of kyphosis, have been measured. The subjects were a group of 34 men and 112 women over 65 years old, without a past history of thyroid disorder, bone metabolic disease, gastrointestinal operation,or malignancy of esophagus and stomach, and who was not taking drugs that influence bone metabolism, such as supplemental calcium, vitamin D, estrogen, bisphosphonate, at the time of investigation. The members of the group were selected among the inpatients and the examinees of the health promotion center of one convalescent hospital and one family medicine department of a general hospital from March of 2006 to August of 2008.
Results: Among the entire 146 subjects, both the RE patient group and HH patient group showed significantly high Cobb angle compared with the normal group (P＜0.001, P=0.002), and the mean age was significantly higher in the HH patient group (P=0.016). However, the result of multiple logistic regression analysis with RE and HH as dependent variables in regard to age, sex, body mass index(BMI), Cobb angle, smoking, alcohol, diabetes mellitus (DM), and vertebral fracture showed that only the Cobb angle showed significant correlation with RE and HH (odds ratio (OR): 1.08 and 1.05, 95%confidence interval (CI): 1.04∼1.13 and 1.01∼1.09). Moreover, when analyzed by dividing the group in two, male and female, the Cobb angle showed a significant correlation with RE and HH (OR: 1.09 and 1.04, 95% CI: 1.04∼1.15 and 1.00∼1.09) in the female group (112 persons) and HH showed a significant correlation with age (OR: 1.10, 95% CI: 1.01∼1.20) also in the female group. Mean while, in the male group (34 persons) the Cobb angle showed a significant correlation with HH only (OR:1.09, 95% CI: 1.00∼1.19).
Conslusion: Kyphosis shows a significant correlation with the occurrence of RE and HH, but there exists some difference depending on sex.
|
|
|
KEYWORD
|
|
|
Kyphosis, Vertebral fracture, Gastro-esophageal reflux disease (GERD), Reflux esophagitis, Hiatal hernia, Elderly
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|